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Candesartan ester of the prevention and treatment of severe adverse reactions
source:Vitalpharms Company Ltd.    Release date:2017/12/6 11:14:02

Candesartan ester piece in the body quickly is hydrolyzed into active metabolite candesartan. Candesartan for angiotensin II AT1 receptor antagonist, by combined with vascular smooth muscle of AT1 receptor antagonist of angiotensin II vasoconstriction, reducing peripheral vascular resistance. So, candesartan ester has the function to eat how long? Side effects need to stop medicine?

Candesartan ester piece of usage and dosage: oral, 1, 1, general adult 4 to 8 mg 1 time, can increase the dose if necessary to 12 mg, or as directed by the doctor's advice, the largest available 32 mg. In general, 4 mg medication for the first time after breakfast, and then, stop drug 1 day, again repeated medication for 7 days, after 4 ~ 6 hours to spike, slow down.

Candesartan ester piece of basically has the following kinds of serious adverse events, to take the preventive treatment of differences:

1, angioedema: sometimes in the face, lips, tongue, pharynx and larynx edema for symptoms of angioedema, should make a careful observation, see exception, discontinued, and properly handle.

2, syncope, and lost consciousness: excessive step-down may cause syncope and temporarily lose consciousness. In this case, should stop medication, and properly handle. Especially is undergoing hemodialysis patients, strict to limit salt treatment, recently began taking diuretic in patients with blood pressure patients, could be quickly reduce blood pressure. As a result, these patients with candesartan ester therapy should be started taking low dose. If it is necessary to increase the dose, should closely observe the clinical situation, slowly.

3, acute renal failure, acute renal failure may occur, patients should be closely observed. If discovery is unusual, should stop medication, and properly handle.

4, high potassium patients: given may appear high potassium, patients should be closely observed. If discovery is unusual, should stop medication, and properly handle.

5, the deterioration of liver function or jaundice: since may appear (GOT), ALT, AST (GPT), gamma GTP equivalent elevated liver dysfunction or jaundice, made patients should be closely observed. If discovery is unusual, should stop medication, and properly handle.

Saw the above introduction, believe everybody already knows candesartan ester of the prevention and treatment of serious adverse events, if there is not understand place, can consult candesartan ester manufacturer of professional and technical personnel, must be able to solve your problem. Hope these information can help to you.

 


Keywords: candesartan ester, candesartan ester manufacturers

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